From O'Hare Airport:

• Start out traveling Southeast on Arrivals, towards Commercial Vehicles.
• Stay straight to go onto Terminal Return/ Airport exit.
• Take I-190 East ramp towards Chicago Loop.
• Merge onto I-190 East.
• Take I-90 East/ Kennedy Expressway East.
• Take Express Lanes exit on the left towards Armitage Avenue.
• Merge onto 1-90 Express Lane/ I-94 Express Lane/ Kennedy Express Lane.
• Take the East Ohio Street exit.
• Merge onto West Ohio Street, proceed for 8 blocks.
• ESPN Zone is located on the corner of Ohio Street and Wabash Avenue.
  

From Midway Airport:

• Star out traveling South on West Airport Drive.
• Turn Left onto South Cicero Avenue/ Sr-50.
• Take I-55 North ramp.
• Merge onto I-55 North / Stavenson Expressway.
• Take I-90 West/ I-94 West/ Ryan Expressway exit #292 towards Wisconsin.
• Merge onto I-90 West/ I-94 West/ South Rumble Street ramp.
• Merge onto I-90 West / Dan Ryan Expressway West/ I-94 West.
• I-90 West/ Dan Ryan Expressway West/ I-94 West becomes I-90 West/ Kennedy Expressway West/ I-94 west.
• Take Lake Street/ 200 North Exit # 51 A.
• Turn right onto West Lake Street.
• Turn left onto West Upper Wacker Drive.
• Turn Left onto North LaSalle Street.
• North LaSalle Street becomes North LaSalle BLVD.
• Turn Right onto West Ohio Street. Proceed a few blocks.
• ESPN Zone is located on the corner of Ohio Street and Wabash Avenue.